Information system designers must consider the influence of users’ intrinsic motivations, in addition to commonly studied extrinsic motivations, to ensure that users will want to continue using the system. In an attempt to acknowledge this need, several studies have extended models of extrinsic motivation to include intrinsic variables. However, these studies largely downplay the role of users’ intrinsic motivations in predicting system use and how this role differs from the role of extrinsic motivation. The role of met or unmet expectations, as a result of system use, is often left out of extant models, and their function as co-creators in user evaluations has not been sufficiently explained. This area remains understudied even though expectations are a firmly established consequence of motivations and an antecedent of interaction evaluations. This paper addresses these gaps by developing and testing a comprehensive model—the Multi-motive Information Systems Continuance Model (MISC)—that (a) explains more accurately and thoroughly the roles of intrinsic and extrinsic motivations, (b) explains how the fulfillment of intrinsic and extrinsic motivations affects system use outcome variables differently through met expectations, and (c) accounts for the effects of key design constructs.